Intercellular Adhesion Molecule 2 / CD102 (ICAM2) Antibody (PE)
429€ (100 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Intercellular Adhesion Molecule 2 / CD102 (ICAM2) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx140337
tested applications
FCM
Description
ICAM2 Antibody is a Mouse Monoclonal against ICAM2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Intercellular Adhesion Molecule 2 / CD102 (ICAM2) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 10 µl/100 µl of whole blood or 106 cells. Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG2a |
| Clone ID | O791 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P13598 |
| Gene ID | 3384 |
| Alias | Intercellular adhesion molecule 2,CD102,ICAM-2 |
| Background | Antibody anti-ICAM2 |
| Status | RUO |
Descripción
Intercellular adhesion molecule 2 (ICAM2) is a member of the immunoglobulin superfamily and plays an essential role in immune cell trafficking, endothelial integrity, and cell signaling. ICAM-2 is encoded by the ICAM2 gene and, along with other intercellular adhesion molecules, serves as a ligand for leukocyte integrins such as LFA-1 (lymphocyte function-associated antigen-1), facilitating the adhesion and transmigration of leukocytes across endothelial cells. It is broadly expressed on endothelial cells, leukocytes, and various other cell types. ICAM-2 is involved in vascular and immune system homeostasis, with roles extending to inflammation, cancer, and neurological functions. Unlike ICAM-1, which is inducible by inflammatory cytokines, ICAM-2 is constitutively expressed but has been found to increase in certain pathophysiological conditions, especially involving endothelial activation. The stable presence of ICAM-2 on endothelial cells makes it significant for lymphocyte recirculation and endothelial-leukocyte interactions, aiding immune surveillance and response to pathogens.
Related Products
Human ICAM2(Intercellular adhesion molecule 2) ELISA Kit
Ver Producto
Mouse ICAM-2(intercellular adhesion molecule 2) ELISA Kit
Ver Producto