Integrin Beta 1 (ITGB1) Antibody (HRP)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Integrin Beta 1 (ITGB1) Antibody (HRP)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx108991
Tested Applications
ELISA
Description
Integrin beta-1 Antibody (HRP) is a Rabbit Polyclonal antibody against Integrin beta-1 conjugated to HRP.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Integrin Beta 1 (ITGB1) Immunogen: Recombinant rat Integrin beta-1 protein (21-729AA). |
| Host | Rabbit |
| Reactivity | Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P49134 |
| Gene ID | 24511 |
| Alias | CD29,FNRB,MDF2,VLAB,GPIIA,MSK12,VLA-BETA,Integrin beta-1,Fibronectin receptor subunit beta,Glycoprotein Iia,VLA-4 subunit beta |
| Background | Antibody anti-ITGB1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ITGB1, also known as integrin subunit beta 1 or CD29, is a crucial component of integrins, a large family of cell adhesion molecules involved in mediating interactions between cells and the extracellular matrix (ECM). Integrins play a vital role in various cellular processes, including cell adhesion, migration, proliferation, and differentiation. ITGB1, in particular, is an essential β subunit that pairs with multiple α subunits to form a variety of heterodimeric integrins. These integrins facilitate the binding of cells to ECM proteins, such as fibronectin, collagen, and laminin, and are critical for tissue integrity, wound healing, and development. ITGB1 is ubiquitously expressed across many cell types and tissues, including fibroblasts, endothelial cells, epithelial cells, and immune cells, reflecting its broad role in cellular homeostasis and signaling. Its function extends beyond simple adhesion, as ITGB1 integrins are involved in transmitting signals bidirectionally across the cell membrane, influencing cellular behavior based on external cues. Through a process called "outside-in" and "inside-out" signaling, ITGB1 integrins regulate cell motility, polarity, and survival, contributing to embryogenesis, immune responses, and cancer progression.
Productos relacionados
Integrin Beta 1 (ITGB1) Antibody
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been…
Ver producto
Integrin Beta 1 Phospho-Thr789 (ITGB1 pT789) Antibody
Rabbit polyclonal antibody against Integrin beta 1 protein when phosphorylated at Thr789. Immunogen region is C-terminal…
Ver producto
Integrin Beta 1 Phospho-Tyr795 (ITGB1 pY795) Antibody
Rabbit polyclonal antibody against ITGB1 protein. Immunogen region is C-terminal. Specificity is as follows for the reac…
Ver producto