Integrin Alpha X / CD11C (ITGAX) Antibody (PE)
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935106861
info@markelab.com
Precio
429€ (100 tests)
Antibody anti-ITGAX
proveedor
Abbexareference
abx139633Tested Applications
FCMreactivity
Human, Monkeystatus
RUOclonality
MonoclonalDescripción
CD11c Antibody is a Mouse Monoclonal against CD11c.
Background
Integrin Subunit Alpha X (ITGAX), commonly referred to as CD11c, is a member of the integrin family that dimerizes with ITGB2 to form the CR4 receptor. ITGAX is highly expressed on dendritic cells and is used as a hallmark marker for this cell type. It mediates cell adhesion, migration, and antigen presentation by enabling dendritic cells to interact with the extracellular matrix and other immune cells. ITGAX also participates in phagocytosis and immune responses against pathogens by functioning as a complement receptor. Its role in immune regulation makes it a focus in studies of chronic inflammatory diseases, atherosclerosis, and cancer immunology. The protein's expression is also commonly analyzed in histological studies to evaluate dendritic cell populations in various tissues.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human, Monkey
immunogen target
Integrin Alpha X / CD11C (ITGAX)
host
Mouse
isotype
IgG1
conjugation
PE
tested applications
FCM
purification
The conjugate is purified by size-exclusion chromatography.
recommended dilution
FCM: 20 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user.The content of a vial (2 ml) is sufficient for 100 tests.
buffer
Stabilizing PBS solution containing 15 mM sodium azide.
size 1
100 tests
storage
Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze.
or code
ITGAX
dry ice
No
availability
Shipped within 5-12 working days.
alias
CD11C,SLEB6,CD11 antigen-like family member C,Leu M5,Leukocyte adhesion glycoprotein p150,95 alpha chain,Leukocyte adhesion receptor p150,95
uniprot id
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