Integrin Alpha X / CD11C (ITGAX) Antibody
312€ (0.1 mg)
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935106861
info@markelab.com
name
Integrin Alpha X / CD11C (ITGAX) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx139631
tested applications
IHC, FCM, IP
Description
CD11c Antibody is a Mouse Monoclonal against CD11c.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Integrin Alpha X / CD11C (ITGAX) |
| Host | Mouse |
| Reactivity | Human, Monkey |
| Recommended Dilution | Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | S179 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A affinity chromatography. |
| Size 1 | 0.1 mg |
| Tested Applications | IHC, FCM, IP |
| Buffer | PBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P20702 |
| Gene ID | 3687 |
| Alias | CD11C,SLEB6,CD11 antigen-like family member C,Leu M5,Leukocyte adhesion glycoprotein p150,95 alpha chain,Leukocyte adhesion receptor p150,95 |
| Background | Antibody anti-ITGAX |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Integrin Subunit Alpha X (ITGAX), commonly referred to as CD11c, is a member of the integrin family that dimerizes with ITGB2 to form the CR4 receptor. ITGAX is highly expressed on dendritic cells and is used as a hallmark marker for this cell type. It mediates cell adhesion, migration, and antigen presentation by enabling dendritic cells to interact with the extracellular matrix and other immune cells. ITGAX also participates in phagocytosis and immune responses against pathogens by functioning as a complement receptor. Its role in immune regulation makes it a focus in studies of chronic inflammatory diseases, atherosclerosis, and cancer immunology. The protein's expression is also commonly analyzed in histological studies to evaluate dendritic cell populations in various tissues.
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