Integrin Alpha X / CD11C (ITGAX) Antibody

Este producto es parte de ITGAX - integrin subunit alpha X
Product Graph
702€ (100 µg)

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935106861
info@markelab.com
name
Integrin Alpha X / CD11C (ITGAX) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx414593
tested applications
IHC, FCM

Description

Integrin Alpha X (CD11c) Antibody is a Mouse Monoclonal antibody against Integrin Alpha X (CD11c).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Integrin Alpha X / CD11C (ITGAX)
Host
Mouse
Reactivity
Human
Recommended Dilution
Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG2a
Purification
Purified
Size 1
100 µg
Form
Liquid
Tested Applications
IHC, FCM
Buffer
PBS.
Availability
Shipped within 3-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P20702
Alias
CD11C,SLEB6,CD11 antigen-like family member C,Leu M5,Leukocyte adhesion glycoprotein p150,95 alpha chain,Leukocyte adhesion receptor p150,95
Background
Antibody anti-ITGAX
Status
RUO
Note
Concentration: 1.0 mg/ml - 

Descripción

Integrin Subunit Alpha X (ITGAX), commonly referred to as CD11c, is a member of the integrin family that dimerizes with ITGB2 to form the CR4 receptor. ITGAX is highly expressed on dendritic cells and is used as a hallmark marker for this cell type. It mediates cell adhesion, migration, and antigen presentation by enabling dendritic cells to interact with the extracellular matrix and other immune cells. ITGAX also participates in phagocytosis and immune responses against pathogens by functioning as a complement receptor. Its role in immune regulation makes it a focus in studies of chronic inflammatory diseases, atherosclerosis, and cancer immunology. The protein's expression is also commonly analyzed in histological studies to evaluate dendritic cell populations in various tissues.

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