Integrin Alpha D / CD11D (ITGAD) Antibody
273€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Integrin Alpha D / CD11D (ITGAD) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx130238
tested applications
WB, IHC, IF/ICC
Description
Integrin Alpha D Antibody is a Rabbit Polyclonal against Integrin Alpha D.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Integrin Alpha D / CD11D (ITGAD) |
| Host | Rabbit |
| Reactivity | Rat |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ADB2,CD11D,Integrin alpha-D,CD11 antigen-like family member D,Leukointegrin alpha D |
| Background | Antibody anti-ITGAD |
| Status | RUO |
Descripción
ITGAD (integrin subunit alpha D), also known as CD11d, is a member of the integrin family of cell adhesion molecules. Integrins are heterodimeric receptors consisting of an alpha and a beta subunit, which mediate cell-cell and cell-extracellular matrix interactions. ITGAD pairs with the beta-2 integrin subunit (CD18) to form the αDβ2 (CD11d/CD18) integrin. This integrin is predominantly expressed on myeloid cells, including macrophages, dendritic cells, monocytes, and natural killer (NK) cells, as well as certain subpopulations of lymphocytes. ITGAD, as part of the β2 integrin subfamily, plays a critical role in immune responses, particularly in cell adhesion, migration, and phagocytosis. ITGAD is the least well-characterized among the beta-2 integrins, but emerging research has highlighted its significance in specialized immune responses, such as the clearance of apoptotic cells, regulation of inflammation, and leukocyte recruitment to chronic inflammatory sites. Additionally, ITGAD has been implicated in processes such as tissue remodeling and wound healing. Due to its involvement in these crucial immune processes, ITGAD has garnered increasing attention in the study of immune system regulation and pathologies, including chronic inflammation, autoimmune diseases, and cancer.
Related Products
ITGAD antibody
Ver Producto
Human Integrin Alpha D / CD11D (ITGAD) Protein
Human Integrin Alpha D (ITGaD) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto
Mouse Integrin Alpha D / CD11D (ITGAD) Protein
Mouse Integrin Alpha D (ITGaD) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Ver Producto