Integrin Alpha 5 Cleaved-Glu895 Light Chain (ITGA5 (Cleaved-E895)) Antibody
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935106861
info@markelab.com
Precio
52€ (10 µg)
Antibody anti-ITGA5
proveedor
Abbexareference
abx015591Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Rabbit polyclonal antibody against ITGA5 protein. Immunogen region is C-terminal. Specificity is as follows for the reactive species: H:E895.
Background
Integrin subunit alpha 5 (ITGA5) is a critical component of the integrin family of transmembrane receptors, responsible for mediating interactions between cells and the extracellular matrix (ECM). ITGA5 pairs with integrin subunit beta 1 (ITGB1) to form the α5β1 integrin, also known as the fibronectin receptor. This integrin complex plays an essential role in cell adhesion, migration, proliferation, and survival by binding to fibronectin, an ECM glycoprotein. ITGA5-mediated interactions are important for various physiological processes, including embryonic development, wound healing, angiogenesis, and the regulation of cell differentiation. Dysregulation of ITGA5 has been implicated in several pathologies, such as fibrosis, cancer, and inflammatory diseases.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Integrin Alpha 5 Cleaved-Glu895 Light Chain (ITGA5 (Cleaved-E895))
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
recommended dilution
WB: 1/500 - 1/3000, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
size 1
10 µg
size 2
100 µg
size 3
200 µg
size 4
300 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ITGA5
dry ice
No
availability
Shipped within 5-10 working days.
alias
FNRA,CD49e,VLA-5,VLA5A,Integrin alpha-5,Integrin alpha-5,Fibronectin receptor subunit alpha,Integrin alpha-F
uniprot id
note
Concentration: 1 mg/ml -
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