ITGA5 antibody

Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
ITGA5 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04347
tested applications
ELISA, WB
Description
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site(site 2) which is distinct from the classical ligand-binding site(site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1(PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1(FBN1) and mediates R-G-D-dependent cell adhesion to FBN1(PubMed:12807887, PubMed:17158881).
Documents del producto
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | integrin, alpha 5 (ITGA5)  | 
| Host | Rabbit  | 
| Reactivity | Human, Rat, Mouse, Monkey  | 
| Recommended Dilution | WB: 1:500-1:2000  | 
| Clonality | polyclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG  | 
| Observed MW | 120 kDa  | 
| Purity | ≥95% as determined by SDS-PAGE  | 
| Purification | Immunogen affinity purified  | 
| Size 1 | 100µg  | 
| Form | liquid  | 
| Tested Applications | ELISA, WB  | 
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)  | 
| UniProt ID | P08648  | 
| Alias | FNRA,CD49e,VLA-5,VLA5A,Integrin alpha-5,Integrin alpha-5,Fibronectin receptor subunit alpha,Integrin alpha-F  | 
| Background | Antibody anti-ITGA5  | 
| Status | RUO  | 
| Note | Mol. Weight 120 kDa  | 
Descripción
Related Products

Human ITGA5 (Integrin alpha-5) ELISA Kit
Ver Producto
ITGA5 antibody
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site(site 2) which is distinct from the classical ligand-binding site(site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1(PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1(FBN1) and mediates R-G-D-dependent cell adhesion to FBN1(PubMed:12807887, PubMed:17158881).
Ver Producto