Insulin-Like Growth Factor I (IGF1) Antibody
195€ (20 µl)
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name
Insulin-Like Growth Factor I (IGF1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx000680
tested applications
ELISA, WB, IHC
Description
Insulin Like Growth Factor 1 (IGF1) Antibody is a Rabbit Polyclonal antibody against Insulin Like Growth Factor 1 (IGF1). Insulin Like Growth Factor 1 (IGF1), also named as IBP1, MGF, IGF-IA and Somatomedin-C, belongs to the insulin family. Insulin Like Growth Factor 1 (IGF1) is structurally and functionally related to insulin but have a much higher growth-promoting activity. Altered expression or mutation of Insulin Like Growth Factor 1 (IGF1) is associated with several human disorders, including type I diabetes and various forms of cancer. Defects in Insulin Like Growth Factor 1 (IGF1) are the cause of insulin-like growth factor I deficiency (Insulin Like Growth Factor 1 (IGF1) deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. The antibody is specific to isoform Insulin Like Growth Factor 1 (IGF1)A.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Insulin-Like Growth Factor I (IGF1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/1500 - 1/3000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.09% NaN3, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P05019 |
| Gene ID | 3479 |
| NCBI Accession | NP_000609.1 |
| OMIM | 147440 |
| Background | Antibody anti-IGF1 |
| Status | RUO |
Descripción
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The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.
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