Insulin Like Growth Factor Binding Protein 7 (IGFBP7) Antibody (Biotin)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Insulin Like Growth Factor Binding Protein 7 (IGFBP7) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx315410
tested applications
ELISA
Description
IGFBP7 Antibody (Biotin) is a Rabbit Polyclonal against IGFBP7 conjugated to Biotin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Insulin Like Growth Factor Binding Protein 7 (IGFBP7) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q16270 |
| Gene ID | 3490 |
| NCBI Accession | NP_001240764.1, NM_001253835.1, NP_001544.1, NM_001553.2 |
| OMIM | 602867 |
| Alias | AGM,PSF,TAF,FSTL2,IBP-7,MAC25,IGFBP-7,RAMSVPS,IGFBP-7v,IGFBPRP1,IGF-binding protein 7 |
| Background | Antibody anti-IGFBP7 |
| Status | RUO |
Descripción
IGFBP7 is a member of the insulin-like growth factor binding protein family that regulates the availability and activity of insulin-like growth factors (IGFs) by binding to them with high affinity Unlike other IGFBPs, IGFBP7 also binds to insulin, modulating its signaling and promoting metabolic homeostasis IGFBP7 plays a critical role in regulating cell growth, apoptosis, and senescence and has anti-tumorigenic properties by inhibiting the mitogenic effects of IGFs Its expression is downregulated in cancers such as colorectal, breast, and prostate cancer where it acts as a tumor suppressor IGFBP7 also plays roles in cardiovascular health by influencing vascular smooth muscle cell proliferation and in fibrosis by mediating tissue remodeling and extracellular matrix deposition
Related Products
Human IGFBP-7(Insulin-like growth factor-binding protein 7) ELISA Kit
Ver Producto
Mouse IGFBP-7(Insulin-like growth factor-binding protein 7) ELISA Kit
Ver Producto