Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody

292.5€ (80 µl)
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935106861
info@markelab.com
name
Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx025600
tested applications
ELISA, WB, IHC, FCM
Description
This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Insulin Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Size 1 | 80 µl |
Size 2 | 400 µl |
Form | Liquid |
Tested Applications | ELISA, WB, IHC, FCM |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9Y6M1 |
Background | Antibody anti-IGF2BP2 |
Status | RUO |
Descripción
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This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes.
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