Inhibitor of Growth Protein 5 (ING5) Antibody

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Description
ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. [provided by RefSeq].
Documents del producto
Product specifications
| Category | Primary Antibodies | 
| Immunogen Target | Inhibitor of Growth Protein 5 (ING5) | 
| Host | Rabbit | 
| Reactivity | Human | 
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. | 
| Clonality | Polyclonal | 
| Conjugation | Unconjugated | 
| Isotype | IgG | 
| Purification | Purified through a protein A column, followed by peptide affinity purification. | 
| Size 1 | 80 µl | 
| Size 2 | 400 µl | 
| Form | Liquid | 
| Tested Applications | ELISA, WB | 
| Buffer | PBS containing 0.09% sodium azide. | 
| Availability | Shipped within 5-10 working days. | 
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. | 
| Dry Ice | No | 
| UniProt ID | Q8WYH8 | 
| Background | Antibody anti-ING5 | 
| Status | RUO | 
Descripción
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ING5 antibody
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator.
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Inhibitor of Growth Protein 5 (ING5) Antibody
ING5 Antibody is a Rabbit Polyclonal antibody against ING5. The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.
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Inhibitor of Growth Protein 5 (ING5) Antibody
ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. [provided by RefSeq].
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