Immunoglobulin Superfamily Member 5 (IGSF5) Antibody

Name: Immunoglobulin Superfamily Member 5 (IGSF5) Antibody
Brand: Abbexa
SKU: abx025805
Price: 281.25 EUR
Availability: OnlineOnly

Este producto es parte de IGSF - immunoglobulin superfamily member

Pida mas información

935106861

info@markelab.com

Precio

281.25€ (80 µl)

Antibody anti-IGSF5

proveedor

Abbexa

reference

abx025805

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity).

Background

IGSF5, also known as Junctional Adhesion Molecule-Like (JAML), is a transmembrane protein involved in immune responses and epithelial integrity. It contains immunoglobulin (Ig)-like domains that mediate interactions with other adhesion molecules and receptors. IGSF5 is expressed in epithelial cells and immune cells, such as γδ T cells, where it facilitates cell adhesion and immune surveillance. Functionally, IGSF5 contributes to tissue repair, immune cell activation, and barrier integrity. Dysregulation of IGSF5 is linked to inflammatory diseases and tissue damage, particularly in the gut and skin.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Immunoglobulin Superfamily Member 5 (IGSF5)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB

purification

Purified through a protein A column, followed by peptide affinity purification.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

IGSF5

dry ice

availability

Shipped within 5-10 working days.

alias

GSF5,JAM4,Junctional adhesion molecule 4

uniprot id

https://www.uniprot.org/uniprotkb/Q9NSI5

note

This product is for research use only.

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