Immunoglobulin Kappa Variable 1-5 (IGKV1-5) Antibody
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Description
IGKV1-5 Antibody is a Rabbit Polyclonal against IGKV1-5.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Immunoglobulin Kappa Variable 1-5 (IGKV1-5) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01602 |
| Background | Antibody anti-IGKV1-5 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
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IGKV1-5 antibody
V segment of the variable domain of immunoglobulins light chain that participates to the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens(PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen(PubMed:20176268, PubMed:17576170).
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Immunoglobulin Kappa Variable 1-5 (IGKV1-5) Antibody
Immunoglobulin Kappa Variable 1-5 Antibody is a Rabbit Polyclonal antibody against Immunoglobulin Kappa Variable 1-5.
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Immunoglobulin Kappa Variable 1-5 (IGKV1-5) Antibody
IGKV1-5 Antibody is a Rabbit Polyclonal against IGKV1-5.
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