IL6R (partial) Peptide
325€ (5 mg)
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Name
IL6R (partial) Peptide
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx266289
Description
Interleukin-6 Receptor (partial) is a peptide.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | IL6R |
| Conjugation | Unconjugated |
| Observed MW | 1216.32 Da |
| Purity | > 95% (HPLC) |
| Size 1 | 5 mg |
| Size 2 | 10 mg |
| Size 3 | 25 mg |
| Form | Lyophilized |
| Buffer | Not applicable. |
| Availability | Shipped within 10-20 working days. |
| Storage | Store dry at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | IL6Q,gp80,CD126,HIES5,IL-6R,IL6RA,IL6RQ,IL-1Ra,IL-6RA,IL6QTL,IL-6R-1,L-6R-Alpha,IL-6Rα |
| Background | Protein IL6R |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
IL6R is a key component of the interleukin-6 (IL6) signaling pathway, consisting of a membrane-bound and soluble form (sIL6R), which binds IL6 and mediates downstream effects via the gp130 co-receptor This interaction activates the JAK/STAT3, MAPK, and PI3K/AKT pathways, regulating immune responses, inflammation, and hematopoiesis IL6R signaling is critical in acute-phase responses, B cell maturation, and T cell proliferation Dysregulation of IL6R activity is implicated in chronic inflammatory diseases such as rheumatoid arthritis, inflammatory bowel disease, and systemic lupus erythematosus (SLE) In cancer, IL6R signaling supports tumor progression, angiogenesis, and immune evasion Therapeutic targeting of IL6R, such as with tocilizumab, is effective in reducing inflammation and cytokine storm in conditions like COVID-19, autoimmune disorders, and hematological malignancies
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