IGF1R / INSR (pY1161) Antibody

Product specifications

Primary Antibodies

IGF1R/INSR (pY1161)

Rabbit

Human, Mouse, Rat

ELISA: 1/40000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

IgG

Purified by affinity chromatography.

50 µg

100 µg

Liquid

ELISA, WB, IHC, IF/ICC

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Shipped within 5-10 working days.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

P08069, P06213

Insulin-like growth factor 1 receptor,IGFR,CD221,IGFIR,JTK13,IGF-I receptor

Antibody anti-IGF1R

RUO

Descripción

The insulin-like growth factor 1 receptor (IGF1R) is a transmembrane receptor that plays a crucial role in cellular growth, survival, and metabolism. It is activated primarily by insulin-like growth factor 1 (IGF-1), a hormone structurally similar to insulin but with distinct biological functions. IGF1R is a member of the receptor tyrosine kinase (RTK) family, which includes receptors like the insulin receptor (INSR). IGF1R signaling is essential for normal development and is involved in many physiological processes, such as cell differentiation, proliferation, and apoptosis inhibition. This receptor is also significant in pathological states, especially cancer, where it can drive tumor growth and metastasis through enhanced cell survival and proliferation pathways.

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