Iduronate 2-Sulfatase (IDS) Antibody
351€ (100 µg)
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name
Iduronate 2-Sulfatase (IDS) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx375949
tested applications
ELISA, WB
Description
Iduronate 2-Sulfatase (IDS) Antibody is a Rabbit Polyclonal antibody against Iduronate 2-Sulfatase (IDS).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Iduronate 2-Sulfatase (IDS) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P22304 |
| Gene ID | 3423 |
| Background | Antibody anti-IDS |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).
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