Hydroxymethylglutaryl-CoA Lyase, Mitochondrial (HMGCL) Antibody

312€ (60 µl)
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935106861
info@markelab.com
name
Hydroxymethylglutaryl-CoA Lyase, Mitochondrial (HMGCL) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx007133
tested applications
IHC
Description
HMGCL Antibody is a Rabbit Polyclonal Antibody against HMGCL.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | Hydroxymethylglutaryl-CoA Lyase, Mitochondrial (HMGCL)  | 
| Host | Rabbit  | 
| Reactivity | Human, Mouse, Rat  | 
| Recommended Dilution | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.  | 
| Clonality | Polyclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG  | 
| Purification | Purified by affinity chromatography.  | 
| Size 1 | 60 µl  | 
| Size 2 | 120 µl  | 
| Size 3 | 200 µl  | 
| Form | Liquid  | 
| Tested Applications | IHC  | 
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.  | 
| Availability | Shipped within 5-10 working days.  | 
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.  | 
| Dry Ice | No  | 
| UniProt ID | P35914  | 
| Gene ID | 3155  | 
| NCBI Accession | NP_000182.2  | 
| Background | Antibody anti-HMGCL  | 
| Status | RUO  | 
| Note | Concentration: 1 mg/ml -  | 
Descripción
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The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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