3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 1 (HSD3B1) Antibody

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Description
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta (5) ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta, 17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta, 17 beta-diol to 5-alpha-dihydrotestosterone.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | 3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 1 (HSD3B1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Size 1 | 80 µl |
Size 2 | 400 µl |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P14060 |
Gene ID | 3283 |
OMIM | 109715 |
Background | Antibody anti-HSD3B1 |
Status | RUO |
Descripción
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3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta (5) ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta, 17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta, 17 beta-diol to 5-alpha-dihydrotestosterone.
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