Hydroperoxide Isomerase ALOXE3 (ALOXE3) Antibody

Descripción

ALOXE3 is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R, 12R-epoxyeicosa-5Z, 9E, 14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Hydroperoxide Isomerase ALOXE3 (ALOXE3)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC

purification

Purified through a protein A column, followed by peptide affinity purification.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

ALOXE3

dry ice

availability

Shipped within 5-10 working days.

alias

Epidermis-type lipoxygenase 3

uniprot id

https://www.uniprot.org/uniprotkb/Q9BYJ1

note

This product is for research use only.

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