Human Zinc finger MIZ domain-containing protein 1 (ZMIZ1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Zinc finger MIZ domain-containing protein 1 (ZMIZ1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx554402
tested applications
ELISA
Description
Human Zinc finger MIZ domain-containing protein 1 (ZMIZ1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Zinc finger MIZ domain-containing protein 1 (ZMIZ1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Zinc finger MIZ domain-containing protein 1 (ZMIZ1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9ULJ6 |
| Alias | MIZ,NEDDFSA,RAI17,TRAFIP10,ZIMP10,PIAS-like protein Zimp10,Retinoic acid-induced protein 17 |
| Background | Elisa kits for ZMIZ1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Zinc Finger MIZ-Type Containing 1 (ZMIZ1) is a transcriptional co-activator and a member of the PIAS-like (protein inhibitor of activated STAT) family which regulates transcription by interacting with transcription factors and chromatin-modifying proteins ZMIZ1 contains a MIZ domain that mediates protein-protein interactions and is involved in enhancing the activity of androgen receptors (AR) SMAD proteins and p53 signaling pathways It contributes to cell proliferation and differentiation particularly in immune cells and hematopoietic stem cells Aberrant expression or mutations in ZMIZ1 have been associated with cancers such as leukemia and breast cancer due to its role in activating oncogenic pathways ZMIZ1 is also implicated in autoimmune diseases such as systemic lupus erythematosus and multiple sclerosis where it influences T-cell activation and immune tolerance highlighting its role in transcriptional regulation and immune homeostasis
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