Human WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1 (WFIKKN1) ELISA Kit
715€ (96 tests)
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935106861
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name
Human WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1 (WFIKKN1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx555880
tested applications
ELISA
Description
Human WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1 (WFIKKN1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1 concentrations in serum, plasma and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1 (WFIKKN1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | < 40 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96NZ8 |
| Alias | RJD2,WFIKKNL,WFDC20A,C16orf12,Growth and differentiation factor-associated serum protein 2,GASP-2,hGASP-2 |
| Background | Elisa kits for WFIKKN1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
WAP follistatin/kazal immunoglobulin kunitz and netrin domain containing 1 (WFIKKN1) is a secreted multidomain protease inhibitor that plays a key role in regulating extracellular proteolytic activity. This protein contains multiple functional domains, including WAP (whey acidic protein), follistatin, kazal, immunoglobulin, kunitz, and netrin-like domains, which collectively enable it to bind and inhibit a wide range of proteases such as trypsin, chymotrypsin, and matrix metalloproteinases. WFIKKN1 is highly expressed in musculoskeletal tissues and acts as a regulator of tissue remodeling, particularly in processes involving myostatin, a negative regulator of muscle growth. By inhibiting myostatin, WFIKKN1 contributes to muscle development and repair. It is also involved in wound healing, fibrosis, and cancer progression, where protease regulation is critical. Dysregulation of WFIKKN1 expression is associated with pathological conditions such as fibrosis, where excessive extracellular matrix deposition occurs, and certain cancers, where it may modulate tumor invasion and metastasis. Ongoing research aims to explore its potential as a therapeutic target for enhancing muscle mass in muscular dystrophies and mitigating tissue damage in chronic inflammatory diseases.
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