Human Vesicle Associated Membrane Protein Associated Protein A (VAPA) Protein

195€ (10 µg)
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name
Human Vesicle Associated Membrane Protein Associated Protein A (VAPA) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069664
tested applications
WB, SDS-PAGE
Description
Recombinant Vesicle Associated Membrane Protein Associated Protein A (VAPA) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Vesicle Associated Membrane Protein Associated Protein A (VAPA) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 16.2 kDa Observed MW (SDS-PAGE): 17 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met-Met132 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9P0L0 |
| Background | Protein VAPA |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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VAPA antibody
Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:25447204). With OSBPL3, may regulate ER morphology(PubMed:16143324). May play a role in vesicle trafficking(PubMed:11511104, PubMed:19289470).
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