VAPA antibody

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935106861
info@markelab.com
name
VAPA antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09369
tested applications
ELISA, WB, IHC, IF, IP
Description
Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:25447204). With OSBPL3, may regulate ER morphology(PubMed:16143324). May play a role in vesicle trafficking(PubMed:11511104, PubMed:19289470).
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | VAMP(vesicle-associated membrane protein)-associated protein A, 33kDa (VAPA) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:5000; IHC: 1:50-1:200;IF: 1:10-1:100; IP: 1:500-1:5000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 33 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF, IP |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q9P0L0 |
Gene ID | 9218 |
Alias | Vesicle-associated membrane protein-associated protein A (VAMP-A, VAMP-associated protein A, VAP-A),33 kDa VAMP-associated protein (VAP-33),VAPA,VAP33 |
Background | Antibody anti-VAPA |
Status | RUO |
Note | Mol. Weight 33 kDa |
Descripción
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VAPA antibody
Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:25447204). With OSBPL3, may regulate ER morphology(PubMed:16143324). May play a role in vesicle trafficking(PubMed:11511104, PubMed:19289470).
Ver Producto