Human UBX Domain-Containing Protein 7 (UBXN7) ELISA Kit

Product specifications

ELISA Kits

UBX Domain-Containing Protein 7 (UBXN7)

Human

Colorimetric

Quantitative

0.156 ng/ml - 10 ng/ml

Optimal dilutions/concentrations should be determined by the end user.

96 tests

Lyophilized

ELISA

Tissue homogenates, cell lysates and other biological fluids.

Shipped within 5-15 working days. The validity for this kit is 6 months.

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

No

O94888

UBXD7,KIAA0794,UBXD7

Elisa kits for UBXN7

RUO

Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

UBX domain protein 7 (UBXN7) is a multifunctional UBX-containing protein that interacts with p97/VCP to regulate protein degradation, ubiquitin-proteasome pathways, and cellular stress responses UBXN7 serves as an adaptor protein, linking p97 to ubiquitin ligases and deubiquitinases to facilitate the extraction and turnover of ubiquitinated proteins It plays a key role in endoplasmic reticulum-associated degradation (ERAD), ensuring the removal of misfolded or damaged proteins from the ER membrane UBXN7 is also involved in the regulation of DNA damage repair, where it coordinates p97 activity to remove ubiquitinated repair proteins, thereby maintaining genome stability Dysregulation of UBXN7 has been implicated in cancer, where its role in protein turnover and DNA repair supports tumor growth and survival UBXN7 is further linked to neurodegenerative diseases, where impaired p97 activity and protein clearance result in toxic protein aggregates Its ability to regulate protein homeostasis and genome stability highlights UBXN7’s critical function in cellular quality control and stress management pathways

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