Human UBX domain-containing protein 2A (UBXN2A) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human UBX domain-containing protein 2A (UBXN2A) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx552419
tested applications
ELISA
Description
Human UBX domain-containing protein 2A (UBXN2A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human UBX domain-containing protein 2A (UBXN2A) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | UBX domain-containing protein 2A (UBXN2A) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P68543 |
| Gene ID | 165324 |
| Alias | UBXD4,UBX domain-containing protein 4 |
| Background | Elisa kits for UBXN2A |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
UBX domain protein 2A (UBXN2A) is a p97/VCP-interacting protein containing a UBX domain that regulates protein degradation pathways including endoplasmic reticulum-associated degradation (ERAD) and ubiquitin-proteasome systems UBXN2A acts as a cofactor for p97, facilitating the extraction and degradation of misfolded proteins and maintaining proteostasis under cellular stress conditions It also modulates autophagy by linking p97 to lysosomal pathways, ensuring the clearance of protein aggregates Dysregulation of UBXN2A expression has been linked to cancer progression, where its involvement in protein turnover supports tumor cell survival, metastasis, and resistance to therapy Emerging studies show that UBXN2A is critical for cellular stress responses, DNA repair, and apoptosis regulation in response to proteotoxic insults UBXN2A’s role in proteasome-mediated degradation and its influence on cellular homeostasis underscore its importance in neurodegeneration and cancer-related proteostasis dysfunction
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