Human UBX Domain-Containing Protein 11 (UBXN11) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human UBX Domain-Containing Protein 11 (UBXN11) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx384102
tested applications
ELISA
Description
Human UBX Domain-Containing Protein 11 (UBXN11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human UBXN11 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | UBX Domain-Containing Protein 11 (UBXN11) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q5T124 |
| Gene ID | 91544 |
| OMIM | 609151 |
| Alias | COA-1,PP2243,SOC,SOCI,UBXD5,Colorectal tumor-associated antigen,UBX domain-containing protein 5 |
| Background | Elisa kits for UBXN11 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
UBX domain protein 11 (UBXN11) is a member of the UBX family of proteins that interact with p97/VCP, a central ATPase in protein degradation and cellular quality control pathways The UBX domain in UBXN11 enables its binding to p97, facilitating the regulation of processes like endoplasmic reticulum-associated degradation (ERAD), protein turnover, and ubiquitin-proteasome pathways UBXN11 also plays a role in autophagy by modulating protein extraction and lysosomal targeting during cellular stress Its involvement in maintaining proteostasis ensures the removal of misfolded or aggregated proteins, critical for cell survival Dysregulation of UBXN11 is linked to neurodegenerative diseases such as Alzheimer’s and Huntington’s, where defective protein clearance contributes to disease progression UBXN11 is also implicated in cancer biology, where its role in protein turnover and stress response can influence tumor growth, survival, and therapy resistance Emerging evidence highlights its potential function in cellular signaling pathways, particularly those associated with proteotoxic stress, autophagy, and DNA damage repair
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