Human Type-1 Angiotensin II Receptor (AGTR1) Protein

Pida mas información
935106861
info@markelab.com
Precio
247€ (10 µg)
Protein AGTR1
proveedor
Abbexareference
abx652166Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Angiotensin II Receptor 1 (AGTR1) Protein is a Recombinant protein from Human.
Background
AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Type-1 Angiotensin II Receptor (AGTR1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 17.7 kDa Observed MW: 25 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Ile124 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
AGTR1
dry ice
No
availability
Shipped within 5-7 working days.
alias
AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
Human AGTR1(Type-1 angiotensin II receptor) ELISA Kit

proveedor
FineTestreference
EH1872reactivity
humanstatus
RUOPrecio a consultar
Ver másMouse Agtr1b(Type-1B angiotensin II receptor) ELISA Kit

proveedor
FineTestreference
EM0801reactivity
mousestatus
RUOPrecio a consultar
Ver másMouse AT1R (angiotensin Ⅱ receptor type 1) ELISA Kit

proveedor
FineTestreference
EM1911reactivity
mousestatus
RUOPrecio a consultar
Ver más