Human Type-1 Angiotensin II Receptor (AGTR1) Protein

Este producto es parte de AGTR1 - Angiotensin II receptor type 1
Human Type-1 Angiotensin II Receptor (AGTR1) Protein

Pida mas información

935106861

info@markelab.com

Precio

247€ (10 µg)

Protein AGTR1

proveedor

Abbexa

reference

abx652166

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Angiotensin II Receptor 1 (AGTR1) Protein is a Recombinant protein from Human.


Background

AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Type-1 Angiotensin II Receptor (AGTR1)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 17.7 kDa Observed MW: 25 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Ile124 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

AGTR1


dry ice

No


availability

Shipped within 5-7 working days.


alias

AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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