Human Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) Protein (Active)
247€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) Protein (Active)
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx600060
Tested Applications
SDS-PAGE
Description
Human Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) Protein is a recombinant Human protein produced in Mammalian cells.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) |
| Host | Mammalian cells |
| Assay Type | Activity: Active Biological Activity: Biological activity was measured by binding ability in functional ELISA. EC50: 0.31-0.57 ng/ml. Sequence Fragment: 1-54 AA. Tag: C-terminal hFc tag |
| Origin | Human |
| Observed MW | Calculated MW: 34.8 kDa Observed MW: 34 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Buffer | PBS, pH 7.4, containing 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store between -20 °C and -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q02223 |
| Gene ID | 608 |
| Alias | Tumor necrosis factor receptor superfamily member 17,BCM,BCMA,CD269,TNFRSF13A,B-cell maturation protein |
| Background | Protein TNFRSF17 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: Not tested Concentration: 0.5 mg/ml |
Background
TNFRSF17, also known as B-cell maturation antigen (BCMA), is a receptor within the tumor necrosis factor receptor superfamily (TNFRSF). It is primarily expressed on B cells, specifically on mature and plasma B cells, where it plays a pivotal role in B cell survival, differentiation, and immunoglobulin secretion. TNFRSF17 is unique among TNFRSF members because of its specificity for binding ligands like APRIL (A Proliferation-Inducing Ligand) and BAFF (B-cell Activating Factor), which are members of the TNF ligand superfamily. BCMA is essential for maintaining long-lived plasma cells and for regulating immune responses, particularly in the context of adaptive immunity. TNFRSF17, also known as B-cell maturation antigen (BCMA), is a receptor within the tumor necrosis factor receptor superfamily (TNFRSF). It is primarily expressed on B cells, specifically on mature and plasma B cells, where it plays a pivotal role in B cell survival, differentiation, and immunoglobulin secretion. TNFRSF17 is unique among TNFRSF members because of its specificity for binding ligands like APRIL (A Proliferation-Inducing Ligand) and BAFF (B-cell Activating Factor), which are members of the TNF ligand superfamily. BCMA is essential for maintaining long-lived plasma cells and for regulating immune responses, particularly in the context of adaptive immunity.
Productos relacionados
Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) Antibody
Rabbit Polyclonal against the TNFRSF17 protein.…
Ver producto
Mouse Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) Protein
Mouse Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) is a recombinant Mouse protein expressed in E. co…
Ver producto
Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) Antibody
Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17).…
Ver producto