Human Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B) ELISA Kit
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935106861
info@markelab.com
Precio
643.5€ (96 tests)
Elisa kits for TNFRSF10B
proveedor
Abbexareference
abx585195Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B) concentrations in serum, plasma, cell lysates and other biological fluids.
Background
TNFRSF10B (TNF receptor superfamily member 10b), also known as TRAIL-R2, DR5 (death receptor 5), or KILLER (Killer/DR5), is a cell surface receptor in the TNF receptor superfamily. It plays a crucial role in mediating apoptosis, especially in transformed or cancerous cells, through interaction with the TNF-related apoptosis-inducing ligand (TRAIL). Like other members of the death receptor family, TNFRSF10B is part of the body's natural mechanism for controlling cell growth, immune responses, and tumor suppression. TRAIL selectively targets cells exhibiting TNFRSF10B expression, making it a key pathway in immune surveillance and tumor inhibition, while leaving normal cells relatively unaffected. Due to its selective induction of apoptosis in abnormal cells, TNFRSF10B has become an important target in cancer therapeutics.
Características del producto
category
ELISA Kits
immunogen target
Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B)
reactivity
Human
test range
15.6 pg/ml - 1000 pg/ml
sensitivity
< 5.9 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
DR5,CD262,KILLER,TRICK2,TRICKB,ZTNFR9,TRAILR2,TRICK2A,TRICK2B,TRAIL-R2,KILLER/DR5,Death receptor 5,TNF-related apoptosis-inducing ligand receptor 2
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TNFRSF10B
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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