Human Tumor Necrosis Factor Ligand Superfamily Member 8 (TNFSF8) Protein

Este producto es parte de TNFSF8 - TNF superfamily member 8
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377€ (20 µg)

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935106861
info@markelab.com
name
Human Tumor Necrosis Factor Ligand Superfamily Member 8 (TNFSF8) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx694160
tested applications
SDS-PAGE

Description

Tumor Necrosis Factor Ligand Superfamily Member 8 (TNFSF8) protein is a recombinant Human protein expressed in HEK293 cells.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Tumor Necrosis Factor Ligand Superfamily Member 8 (TNFSF8)
Host
HEK293 cells
Assay Type
Activity: Not tested
Sequence Fragment: Gln63-Asp234
Tag: C-terminal His tag
Origin
Human
Observed MW
Calculated MW: 18.81 kDa  Observed MW (SDS-PAGE): 38 kDa
Expression
Recombinant
Purity
>95% (SDS-PAGE)
Size 1
20 µg
Size 2
100 µg
Size 3
500 µg
Size 4
1 mg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80.
Availability
Shipped within 5-15 working days.
Storage
Storage: Store lyophilized between -20 °C and -80°C.
Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months.
Shelf Life: 12 months.
Dry Ice
No
UniProt ID
P32971
Gene ID
944
OMIM
63875
Alias
Tumor necrosis factor ligand superfamily member 8,CD153,CD30L,CD30LG,TNLG3A,




CD30 ligand
Background
Protein TNFSF8
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Reconstitute in sterile H2O. Do not vortex.

Descripción

Tumor Necrosis Factor Superfamily Member 8 (TNFSF8), also known as CD30L, is a membrane-bound cytokine and a member of the tumor necrosis factor (TNF) ligand family. It interacts with CD30, a receptor predominantly expressed on activated T cells and certain cancer cells, to regulate immune responses and cellular proliferation. TNFSF8 plays a role in T-cell activation, differentiation, and apoptosis, particularly in inflammatory and autoimmune processes. Its expression is upregulated in conditions such as Hodgkin's lymphoma, anaplastic large cell lymphoma, and chronic inflammation, making it a target of interest for therapeutic intervention. Dysregulation of TNFSF8 signaling contributes to immune disorders and malignancies, emphasizing its role in maintaining immune system homeostasis.

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