Human Tumor Necrosis Factor Ligand Superfamily Member 8 (TNFSF8) Protein
416€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Tumor Necrosis Factor Ligand Superfamily Member 8 (TNFSF8) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx694160
tested applications
SDS-PAGE
Description
Human Tumor Necrosis Factor Ligand Superfamily Member 8 (TNFSF8) Protein is a recombinant Human protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Host | HEK293 cells |
| Origin | Human |
| Observed MW | Molecular Weight: Calculated MW: 18.81 kDa Observed MW (SDS-PAGE): 38 kDa Sequence Fragment: Gln63-Asp234 Tag: C-terminal His tag |
| Expression | Recombinant |
| Purity | >95% (SDS-PAGE) |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Form | Lyophilized Reconstitute in sterile H2O. Do not vortex. |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store lyophilized between -20 °C and -80 °C. |
| Dry Ice | No |
| UniProt ID | P32971 |
| Gene ID | 944 |
| OMIM | 63875 |
| Alias | Tumor necrosis factor ligand superfamily member 8,CD153,CD30L,CD30LG,TNLG3A, CD30 ligand |
| Background | Protein TNFSF8 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Tumor Necrosis Factor Superfamily Member 8 (TNFSF8), also known as CD30L, is a membrane-bound cytokine and a member of the tumor necrosis factor (TNF) ligand family. It interacts with CD30, a receptor predominantly expressed on activated T cells and certain cancer cells, to regulate immune responses and cellular proliferation. TNFSF8 plays a role in T-cell activation, differentiation, and apoptosis, particularly in inflammatory and autoimmune processes. Its expression is upregulated in conditions such as Hodgkin's lymphoma, anaplastic large cell lymphoma, and chronic inflammation, making it a target of interest for therapeutic intervention. Dysregulation of TNFSF8 signaling contributes to immune disorders and malignancies, emphasizing its role in maintaining immune system homeostasis.
Related Products
CD30 Ligand (TNFSF8) Antibody
Rabbit polyclonal antibody against CD153 protein. Immunogen region is Internal.
Ver Producto
Mouse CD30 Ligand (TNFSF8) ELISA Kit
Mouse CD30 Ligand (TNFSF8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse CD30 Ligand (TNFSF8) concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto
Human CD30 Ligand (TNFSF8) Protein
Human Cluster Of Differentiation 30 Ligand (CD30L) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto