Human Tumor Necrosis Factor Ligand Superfamily Member 8 (TNFSF8) Protein
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935106861
info@markelab.com
Precio
416€ (20 µg)
Protein TNFSF8
proveedor
Abbexareference
abx694160Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Human Tumor Necrosis Factor Ligand Superfamily Member 8 (TNFSF8) Protein is a recombinant Human protein expressed in HEK293 cells.
Background
Tumor Necrosis Factor Superfamily Member 8 (TNFSF8), also known as CD30L, is a membrane-bound cytokine and a member of the tumor necrosis factor (TNF) ligand family. It interacts with CD30, a receptor predominantly expressed on activated T cells and certain cancer cells, to regulate immune responses and cellular proliferation. TNFSF8 plays a role in T-cell activation, differentiation, and apoptosis, particularly in inflammatory and autoimmune processes. Its expression is upregulated in conditions such as Hodgkin's lymphoma, anaplastic large cell lymphoma, and chronic inflammation, making it a target of interest for therapeutic intervention. Dysregulation of TNFSF8 signaling contributes to immune disorders and malignancies, emphasizing its role in maintaining immune system homeostasis.
Características del producto
category
Proteins and Peptides
origin
Human
host
HEK293 cells
host
HEK293 cells
form
Lyophilized Reconstitute in sterile H2O. Do not vortex.
tested applications
SDS-PAGE
size 1
20 µg
size 2
100 µg
observerd MW
Molecular Weight: Calculated MW: 18.81 kDa Observed MW (SDS-PAGE): 38 kDa Sequence Fragment: Gln63-Asp234 Tag: C-terminal His tag
expression
Recombinant
purity
>95% (SDS-PAGE)
buffer
Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80.
storage
Store lyophilized between -20 °C and -80 °C.
or code
TNFSF8
dry ice
No
availability
Shipped within 5-15 working days.
alias
Tumor necrosis factor ligand superfamily member 8,CD153,CD30L,CD30LG,TNLG3A, CD30 ligand
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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