Human CD30 Ligand (TNFSF8) Protein
208€ (10 µg)
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name
Human CD30 Ligand (TNFSF8) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065920
tested applications
WB, SDS-PAGE
Description
Human Cluster Of Differentiation 30 Ligand (CD30L) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | CD30 Ligand (TNFSF8) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 20.6 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu60-Ile227 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P32971 |
| Gene ID | 944 |
| OMIM | 603875 |
| Alias | Tumor necrosis factor ligand superfamily member 8,CD153,CD30L,CD30LG,TNLG3A, CD30 ligand |
| Background | Protein TNFSF8 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Tumor Necrosis Factor Superfamily Member 8 (TNFSF8), also known as CD30L, is a membrane-bound cytokine and a member of the tumor necrosis factor (TNF) ligand family. It interacts with CD30, a receptor predominantly expressed on activated T cells and certain cancer cells, to regulate immune responses and cellular proliferation. TNFSF8 plays a role in T-cell activation, differentiation, and apoptosis, particularly in inflammatory and autoimmune processes. Its expression is upregulated in conditions such as Hodgkin's lymphoma, anaplastic large cell lymphoma, and chronic inflammation, making it a target of interest for therapeutic intervention. Dysregulation of TNFSF8 signaling contributes to immune disorders and malignancies, emphasizing its role in maintaining immune system homeostasis.
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