Human Transmembrane Emp24 Domain Containing Protein 2 (TMED2) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for TMED2
proveedor
Abbexareference
abx383785Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Transmembrane Emp24 Domain Containing Protein 2 (TMED2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human TMED2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
TMED2, a member of the p24 family, functions as a cargo receptor and vesicle trafficking regulator in the early secretory pathway, mediating protein transport between the ER, ER-Golgi intermediate compartment (ERGIC), and Golgi apparatus. It is a key component of the COPII vesicle coat complex, where it assists in the selective packaging and transport of secretory and membrane proteins. TMED2 also regulates the recycling of vesicles back to the ER through interactions with the COPI coat complex, ensuring efficient cargo flow and ER-Golgi communication. It is highly expressed in tissues with active protein secretion and participates in processes such as receptor trafficking, organelle integrity, and cellular homeostasis. Dysregulation of TMED2 has been implicated in developmental defects, metabolic diseases, and cancers, where altered protein sorting disrupts cellular signaling and growth. Knockdown studies show impaired vesicle transport, disrupted Golgi architecture, and ER stress, highlighting its critical role in maintaining vesicular trafficking, protein quality control, and cellular function.
Características del producto
category
ELISA Kits
immunogen target
Transmembrane Emp24 Domain Containing Protein 2 (TMED2)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.094 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
TMED2, RNP24,p24 family protein beta-1,p24beta1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TMED2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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