Human TRAF3-interacting JNK-activating modulator (TRAF3IP3) ELISA Kit
715€ (96 tests)
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935106861
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name
Human TRAF3-interacting JNK-activating modulator (TRAF3IP3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385482
tested applications
ELISA
Description
Human TRAF3-interacting JNK-activating modulator (TRAF3IP3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human TRAF3IP3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | TRAF3-interacting JNK-activating modulator (TRAF3IP3) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9Y228 |
| Gene ID | 80342 |
| OMIM | 608255 |
| Alias | T3JAM,TRAF3-interacting protein 3 |
| Background | Elisa kits for TRAF3IP3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
TRAF3-interacting JNK-activating modulator (TRAF3IP3) is a protein involved in the activation of the c-Jun N-terminal kinase (JNK) signaling pathway, a key regulator of cell stress responses, apoptosis, and immune function. TRAF3IP3 acts as a scaffold that facilitates the recruitment of TRAF proteins and kinases to specific signaling complexes, promoting JNK activation in response to stimuli such as cytokines and stress. It is also involved in modulating immune receptor signaling and contributes to both innate and adaptive immune responses. Dysregulation of TRAF3IP3 expression or function can affect immune homeostasis and has been linked to immune disorders and inflammatory diseases, where excessive JNK activity may drive pathological processes. Emerging studies suggest its potential role in cancer biology, where JNK signaling contributes to tumor growth or suppression depending on the cellular context.
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