Human TRAF3-interacting JNK-activating modulator (TRAF3IP3) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for TRAF3IP3
proveedor
Abbexareference
abx385482Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human TRAF3-interacting JNK-activating modulator (TRAF3IP3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human TRAF3IP3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
TRAF3-interacting JNK-activating modulator (TRAF3IP3) is a protein involved in the activation of the c-Jun N-terminal kinase (JNK) signaling pathway, a key regulator of cell stress responses, apoptosis, and immune function. TRAF3IP3 acts as a scaffold that facilitates the recruitment of TRAF proteins and kinases to specific signaling complexes, promoting JNK activation in response to stimuli such as cytokines and stress. It is also involved in modulating immune receptor signaling and contributes to both innate and adaptive immune responses. Dysregulation of TRAF3IP3 expression or function can affect immune homeostasis and has been linked to immune disorders and inflammatory diseases, where excessive JNK activity may drive pathological processes. Emerging studies suggest its potential role in cancer biology, where JNK signaling contributes to tumor growth or suppression depending on the cellular context.
Características del producto
category
ELISA Kits
immunogen target
TRAF3-interacting JNK-activating modulator (TRAF3IP3)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.094 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
T3JAM,TRAF3-interacting protein 3
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TRAF3IP3
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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