Human Toll Like Receptor 10 (TLR10) Protein

Este producto es parte de TLR10 - toll like receptor 10
Human Toll Like Receptor 10 (TLR10) Protein

Pida mas información

935106861

info@markelab.com

Precio

247€ (10 µg)

Protein TLR10

proveedor

Abbexa

reference

abx168288

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Toll Like Receptor 10 Protein is a recombinant Human protein expressed in E. coli.


Background

Toll-like receptor 10 (TLR10) is the only human TLR with an entirely unknown ligand and functional role, marking it as a unique and enigmatic member of the Toll-like receptor (TLR) family. This family plays essential roles in innate immunity by recognizing pathogen-associated molecular patterns (PAMPs) and initiating immune responses. Despite its unclear ligand specificity, TLR10 is hypothesized to play regulatory roles, particularly in modulating immune responses. In humans, TLR10 is primarily expressed in lymphoid tissues such as the spleen, lymph nodes, tonsils, and the immune cells within these tissues, including B cells, dendritic cells (DCs), and monocytes. TLR10 is expressed alongside TLRs that typically recognize nucleic acids or microbial components, which suggests that it may function in coordination with other TLRs to fine-tune immune responses, potentially acting as a regulatory or inhibitory receptor.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Toll Like Receptor 10 (TLR10)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 52.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Trp617-Glu784 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

TLR10


dry ice

No


availability

Shipped within 5-7 working days.


alias

Toll-like receptor 10,CD290


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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