Human TNFRSF1B (Tumor necrosis factor receptor superfamily member 1B) ELISA Kit
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Name
Human TNFRSF1B (Tumor necrosis factor receptor superfamily member 1B) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH0518
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 7.813-500pg/ml |
| Sensitivity | 4.688pg/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P20333 |
| Alias | Tumor necrosis factor receptor superfamily member 1B,p75,TBPII,TNFBR,TNFR2,CD120b,TNFR1B,TNFR80,TNF-R75,p75TNFR,TNF-R-II,Tumor necrosis factor receptor 2,p80 TNF-alpha receptor |
| Background | Elisa kits for TNFRSF1B |
| Status | RUO |
Background
TNFRSF1B, also known as Tumor Necrosis Factor Receptor Superfamily Member 1B or TNFR2, is a cell surface receptor predominantly expressed on immune cells, including regulatory T cells (Tregs), endothelial cells, and neurons. TNFR2 is one of the two primary receptors for tumor necrosis factor-alpha (TNF-α), along with TNFR1 (TNFRSF1A). Although TNFR1 and TNFR2 both bind TNF-α, they have unique and overlapping roles within immune responses. TNFR2 primarily activates pathways that promote cell survival, tissue regeneration, and anti-inflammatory responses, differentiating it from TNFR1, which is more commonly associated with apoptosis and pro-inflammatory signaling. The TNFRSF1B gene is located on chromosome 1p36.22 and encodes a receptor of 461 amino acids. TNFR2 is a key component in regulating inflammation, modulating T cell activity, and contributing to vascular health. Its interaction with TNF-α can activate both canonical (NF-κB) and non-canonical pathways, resulting in varying cellular responses depending on the cellular environment and receptor activation context.
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