Human Telomerase Reverse Transcriptase (TERT) Protein
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935106861
info@markelab.com
Precio
221€ (10 µg)
Protein TERT
proveedor
Abbexareference
abx069251Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human Telomerase Reverse Transcriptase (TERT) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
Telomerase Reverse Transcriptase (TERT) is the catalytic subunit of the telomerase enzyme complex, responsible for maintaining telomere length by adding telomeric repeats to chromosome ends. TERT is crucial for cellular longevity, stem cell renewal, and genomic stability. It is highly active in embryonic and stem cells but repressed in most somatic cells. Reactivation of TERT is a hallmark of cancer, providing cells with replicative immortality. Beyond telomere maintenance, TERT has non-telomeric roles in transcriptional regulation, mitochondrial function, and resistance to apoptosis. Its misregulation is implicated in aging, cancer, and telomere-related diseases such as dyskeratosis congenita.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Telomerase Reverse Transcriptase (TERT)
host
E. coli
conjugation
Unconjugated
form
Lyophilized Reconstitute in ddH2O to a concentration of 0.1-0.25 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 63.4 kDa Observed MW (SDS-PAGE): 65 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Arg787-Arg1084 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 97%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
TERT
dry ice
No
availability
Shipped within 5-7 working days.
alias
CMM9,DKCA2,DKCB4,EST2,PFBMFT1,TCS1,TP2,TRT hEST2,hTRT,Telomerase-associated protein 2
uniprot id
NCBI accession
NP_001180305.1, NM_001193376.1
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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