Human Telomerase Reverse Transcriptase (TERT) Protein

Este producto es parte de TERT - Telomerase Reverse Transcriptase
Human Telomerase Reverse Transcriptase (TERT) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein TERT

proveedor

Abbexa

reference

abx069251

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Telomerase Reverse Transcriptase (TERT) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

Telomerase Reverse Transcriptase (TERT) is the catalytic subunit of the telomerase enzyme complex, responsible for maintaining telomere length by adding telomeric repeats to chromosome ends. TERT is crucial for cellular longevity, stem cell renewal, and genomic stability. It is highly active in embryonic and stem cells but repressed in most somatic cells. Reactivation of TERT is a hallmark of cancer, providing cells with replicative immortality. Beyond telomere maintenance, TERT has non-telomeric roles in transcriptional regulation, mitochondrial function, and resistance to apoptosis. Its misregulation is implicated in aging, cancer, and telomere-related diseases such as dyskeratosis congenita.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Telomerase Reverse Transcriptase (TERT)


host

E. coli


conjugation

Unconjugated


form

Lyophilized Reconstitute in ddH2O to a concentration of 0.1-0.25 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 63.4 kDa Observed MW (SDS-PAGE): 65 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Arg787-Arg1084 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 97%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

TERT


dry ice

No


availability

Shipped within 5-7 working days.


alias

CMM9,DKCA2,DKCB4,EST2,PFBMFT1,TCS1,TP2,TRT hEST2,hTRT,Telomerase-associated protein 2


NCBI accession

NP_001180305.1, NM_001193376.1


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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