Human Tartrate-Resistant Acid Phosphatase 5 / TRACP5 (ACP5) Protein

Este producto es parte de ACP-Acid Phosphatase
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234€ (10 µg)

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935106861
info@markelab.com
name
Human Tartrate-Resistant Acid Phosphatase 5 / TRACP5 (ACP5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167123
tested applications
WB, SDS-PAGE

Description

Human Acid Phosphatase 5, Tartrate Resistant Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Tartrate-Resistant Acid Phosphatase 5 / TRACP5 (ACP5)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 59.8 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Gln79-Arg318
Tag: N-terminal His tag and GST tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P13686
Alias
HPAP,TRACP5a,TRACP5b,TRAP,TRAcP,TrATPase
Background
Protein ACP5
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Acid phosphatases (ACP) are a group of enzymes that catalyze the hydrolysis of phosphate ester bonds under acidic conditions, resulting in the release of inorganic phosphate from organic molecules. These enzymes are characterized by their ability to function optimally at low pH levels. There are multiple forms of acid phosphatase, often denoted as ACP1, ACP2, ACP3, ACP4, and ACP5. Each isoform may have distinct tissue distribution, substrate specificity, and physiological roles. ACP1. It is found in various tissues and body fluids, including red blood cells, bone, prostate gland, and semen. It is a biomarker for poor prognosis in prostate cancer has been linked to bad clinical prognosis. ACP5 (Tartrate-Resistant Acid Phosphatase - TRAP) is mainly found in bone tissue, particularly in osteoclasts and Involved in bone resorption by osteoclasts, playing a critical role in bone remodeling and calcium homeostasis

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