Human Tartrate-Resistant Acid Phosphatase 5 / TRACP5 (ACP5) Protein

Background

Acid phosphatases (ACP) are a group of enzymes that catalyze the hydrolysis of phosphate ester bonds under acidic conditions, resulting in the release of inorganic phosphate from organic molecules. These enzymes are characterized by their ability to function optimally at low pH levels. There are multiple forms of acid phosphatase, often denoted as ACP1, ACP2, ACP3, ACP4, and ACP5. Each isoform may have distinct tissue distribution, substrate specificity, and physiological roles. ACP1. It is found in various tissues and body fluids, including red blood cells, bone, prostate gland, and semen. It is a biomarker for poor prognosis in prostate cancer has been linked to bad clinical prognosis. ACP5 (Tartrate-Resistant Acid Phosphatase - TRAP) is mainly found in bone tissue, particularly in osteoclasts and Involved in bone resorption by osteoclasts, playing a critical role in bone remodeling and calcium homeostasis