Human T-Lymphocyte Activation Antigen CD80 (CD80) Protein
416€ (20 µg)
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935106861
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name
Human T-Lymphocyte Activation Antigen CD80 (CD80) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx694244
tested applications
SDS-PAGE
Description
Human T-Lymphocyte Activation Antigen CD80 (CD80) Protein is a recombinant Human protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Host | HEK293 cells |
| Origin | Human |
| Observed MW | Molecular Weight: Calculated MW: 26.51 kDa Observed MW (SDS-PAGE): 40 kDa Sequence Fragment: Met1-Asn242 Tag: C-terminal His tag |
| Expression | Recombinant |
| Purity | >95% (SDS-PAGE) |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Form | Lyophilized Reconstitute in sterile H2O. Do not vortex. |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store lyophilized between -20 °C and -80 °C. |
| Dry Ice | No |
| UniProt ID | P33681 |
| Alias | B7,BB1,B7-1,B7.1,LAB7,CD28LG,CD28LG1,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1,T-lymphocyte activation antigen CD80 |
| Background | Protein CD80 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD80, also known as B7-1, is a protein encoded by the CD80 gene in humans. It is an essential costimulatory molecule expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, B cells, and macrophages. CD80 plays a critical role in the regulation of immune responses by providing the necessary second signal for T cell activation and survival. This molecule interacts with CD28 and CTLA-4 receptors on T cells, mediating various immune responses. The discovery and understanding of CD80 have significant implications for immunology, particularly in the context of autoimmune diseases, transplant rejection, and cancer immunotherapy.
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