Human T-Cell Surface Glycoprotein CD3 Gamma Chain (CD3G) ELISA Kit
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935106861
info@markelab.com
Precio
611€ (96 tests)
Elisa kits for CD3G
proveedor
Abbexareference
abx352451Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human T-Cell Surface Glycoprotein CD3 Gamma Chain (CD3G) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human T-Cell Surface Glycoprotein CD3 Gamma Chain (CD3G) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CD3G, the gamma subunit of the T-cell receptor (TCR) complex, is a crucial component of the TCR-CD3 complex, which plays an essential role in T-cell activation, signal transduction, and immune responses. The TCR-CD3 complex is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules on antigen-presenting cells (APCs). This recognition initiates signaling cascades that activate T cells, leading to immune responses such as T-cell proliferation, cytokine production, and differentiation into effector cells. The CD3 complex consists of multiple subunits, including CD3G (gamma), CD3E (epsilon), CD3D (delta), and CD3Z (zeta), which associate with the TCR α/β or γ/δ heterodimers to form the full TCR-CD3 complex. The CD3G gene is located on chromosome 11q23, adjacent to the CD3D gene. It encodes the CD3γ chain, a transmembrane protein that is integral to the structural stability and function of the TCR-CD3 complex. CD3G is expressed on the surface of all mature T lymphocytes and certain natural killer (NK) cells, where it contributes to immune surveillance, host defense against infections, and recognition of transformed cells (e.g., tumor cells).
Características del producto
category
ELISA Kits
immunogen target
T-Cell Surface Glycoprotein CD3 Gamma Chain (CD3G)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
0.1 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
T3G,IMD17,CD3GAMMA,CD3-GAMMA,T-cell surface glycoprotein CD3 gamma chain,T-cell receptor T3 gamma chain
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CD3G
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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