Human T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) ELISA Kit

Este producto es parte de CD3E - CD3 epsilon subunit of T-cell receptor complex
Human T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for CD3E

proveedor

Abbexa

reference

abx386391

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) concentrations in tissue homogenates, cell lysates and other biological fluids.

Background

CD3E (CD3 epsilon) is one of the key subunits of the T-cell receptor (TCR)-CD3 complex, which is vital for T-cell activation and immune responses. The TCR complex allows T lymphocytes to recognize and respond to antigens presented by major histocompatibility complex (MHC) molecules on antigen-presenting cells (APCs). CD3E plays a critical role in assembling the TCR-CD3 complex and facilitating signal transduction after antigen recognition. The CD3E gene is located on chromosome 11q23 and encodes the CD3ε chain, a type I transmembrane protein essential for the assembly, expression, and signaling function of the TCR. Along with other CD3 subunits (CD3δ, CD3γ, and CD3ζ), CD3E forms part of the signal-transducing complex that transmits signals from the TCR upon antigen engagement. This signal initiates the cascade that leads to T-cell activation, differentiation, and proliferation, all of which are crucial for immune defense against pathogens.

Características del producto

category

ELISA Kits

immunogen target

T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

sensitivity

< 0.062 ng/ml

assay type

Sandwich

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates, cell lysates and other biological fluids.

size 1

96 tests

size 2

5 × 96 tests

size 3

10 × 96 tests

alias

T3E,TCRE,IMD18,CD3epsilon,T-cell surface glycoprotein CD3 epsilon chain,T-cell surface antigen T3/Leu-4 epsilon chain

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

CD3E

dry ice

No

uniprot id

https://www.uniprot.org/uniprotkb/Q86VB7

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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reference

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reactivity

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status

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