Human T-cell surface glycoprotein CD1e, membrane-associated (CD1E) ELISA Kit
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Description
Human T-cell surface glycoprotein CD1e, membrane-associated (CD1E) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human T-cell surface glycoprotein CD1e, membrane-associated (CD1E) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | T-cell surface glycoprotein CD1e, membrane-associated (CD1E) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P15812 |
| Gene ID | 913 |
| OMIM | 188411 |
| Alias | R2,CD1A,T-cell surface glycoprotein CD1e membrane-associated,hCD1e,R2G1 |
| Background | Elisa kits for CD1E |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CD1E molecule is a member of the CD1 family of glycoproteins, which are antigen-presenting molecules structurally related to the major histocompatibility complex (MHC) class I proteins. CD1 proteins are unique in their ability to present lipid and glycolipid antigens rather than peptide antigens, which are typically presented by MHC molecules. CD1E plays a specialized role within the CD1 family, particularly in the intracellular processing and presentation of lipid antigens, distinguishing it from other CD1 molecules that are predominantly involved in antigen presentation at the cell surface. CD1E is critical for the proper functioning of lipid antigen presentation, especially in professional antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. While other CD1 family members (e.g., CD1A, CD1B, CD1C, and CD1D) directly present lipid antigens to T cells, CD1E’s primary function is to facilitate the processing of complex lipids into smaller components that can be presented by other CD1 molecules. This intracellular processing is essential for generating the lipid antigens that eventually engage T cells, such as natural killer T (NKT) cells or conventional T cells, in the immune response to pathogens like mycobacteria, fungi, and certain viruses.
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