Human T-cell surface glycoprotein CD1c (CD1C) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Human T-cell surface glycoprotein CD1c (CD1C) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx505734
tested applications
ELISA
Description
Human T-cell surface glycoprotein CD1c (CD1C) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human T-cell surface glycoprotein CD1c (CD1C) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | T-cell surface glycoprotein CD1c (CD1C) |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Test Range | 0.156 ng/ml - 10 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | P29017 |
Gene ID | 911 |
OMIM | 188340 |
Alias | R7,CD1,CD1A,BDCA1,T-cell surface glycoprotein CD1c |
Background | Elisa kits for CD1C |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
The CD1C molecule is a member of the CD1 family of glycoproteins, which play a critical role in the immune system by presenting lipid and glycolipid antigens to T cells. Unlike major histocompatibility complex (MHC) class I and II molecules, which primarily present peptide antigens, CD1 molecules specialize in the presentation of lipids, making them essential players in immune responses against lipid-containing pathogens like mycobacteria. CD1C, in particular, is one of the most studied isoforms in the CD1 family due to its role in presenting antigens to T cells, especially CD1c-restricted T cells, which are important in the defense against bacterial infections, especially those involving mycobacteria. CD1C is expressed predominantly on antigen-presenting cells (APCs), such as dendritic cells, B cells, and macrophages, which are crucial for initiating adaptive immune responses. The molecule plays a significant role in shaping the immune response to lipid antigens, facilitating the recognition and elimination of microbial invaders, especially those with complex lipid envelopes, such as Mycobacterium tuberculosis
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