Human Striatin-4 (STRN4) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Striatin-4 (STRN4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx547800
tested applications
ELISA
Description
Human Striatin-4 (STRN4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Striatin-4 (STRN4) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Striatin-4 (STRN4) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.14 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9NRL3 |
| Alias | Zinedin,ZIN |
| Background | Elisa kits for STRN4 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Striatin-4 (STRN4), also called zinedin, is a scaffolding protein within the striatin family and a core component of the STRIPAK complex, where it regulates PP2A-dependent dephosphorylation and kinase signaling pathways. STRN4 is broadly expressed in tissues, including the brain, heart, and vascular endothelial cells, where it contributes to calcium-calmodulin signaling, cytoskeletal organization, and cell signaling networks. It interacts with proteins involved in cell migration, vesicular trafficking, and angiogenesis, playing a key role in endothelial cell communication and vascular homeostasis. STRN4 is also implicated in neuronal development and synaptic function, modulating calcium signaling and cytoskeletal remodeling. Dysregulation of STRN4 contributes to cancer, cardiovascular diseases, and neurodevelopmental disorders, where its altered activity disrupts cellular signaling and homeostasis. Knockdown studies show impaired cell migration, reduced PP2A activity, and defective cytoskeletal integrity, highlighting its role in coordinating cell signaling, structural organization, and physiological processes.
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