Human Somatostatin Receptor 2 (SSTR2) Protein

Este producto es parte de SSTR - Somatostatin Receptor
Human Somatostatin Receptor 2 (SSTR2) Protein

Pida mas información

935106861

info@markelab.com

Precio

2301€ (1 mg)

Protein SSTR2

proveedor

Abbexa

reference

abx652236

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Somatostatin Receptor 2 (SSTR2) Protein is a Recombinant protein from Human.


Background

SSTR2 is another member of the somatostatin receptor family, primarily activated by somatostatin. Like SSTR1, SSTR2 also couples to Gi proteins to inhibit adenylate cyclase and reduce cAMP levels. It is expressed in a variety of tissues, including the pituitary gland, pancreas, and gastrointestinal tract, and plays a crucial role in regulating the secretion of growth hormone, insulin, and other hormones. SSTR2 is particularly important in inhibiting the release of growth hormone from the pituitary and in controlling insulin release from pancreatic β-cells. It is also implicated in regulating gastrointestinal motility and digestive enzyme secretion. Dysregulation of SSTR2 signaling is often found in tumors, particularly neuroendocrine tumors, where increased hormone secretion occurs. SSTR2 agonists, like somatostatin analogs, are used in the clinical management of conditions such as acromegaly, carcinoid syndrome, and other endocrine-related disorders, where they help control hormone levels and reduce tumor growth.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Somatostatin Receptor 2 (SSTR2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

1 mg


size 2

5 mg


observerd MW

Molecular Weight: Calculated MW: 22.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser31-Leu218 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

SSTR2


dry ice

No


availability

Shipped within 1-2 months.


alias

SSTR2,somatotropin release-inhibiting factor receptor,SRIF-1,SST2


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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