Human SOCS4(Suppressor Of Cytokine Signaling 4) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human SOCS4(Suppressor Of Cytokine Signaling 4) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH4024
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 3.906-250pg/ml |
| Size 1 | 96T |
| Sample Type | Busacar en las instrucciones |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 6 months |
| UniProt ID | Q8WXH5 |
| Alias | SOCS-4,Suppressor of cytokine signaling 7,SOCS-7 |
| Background | Elisa Kits SOCS4 |
| Status | RUO |
SOCS4 is a member of the SOCS protein family that regulates cytokine signaling by inhibiting the Janus kinase (JAK)/STAT pathway and promoting the proteasomal degradation of signaling intermediates via its SOCS box domain. It interacts with phosphorylated cytokine receptors and downstream proteins to suppress excessive cytokine responses, particularly in pathways related to epidermal growth factor receptor (EGFR) and interleukin-4 (IL-4). SOCS4 is broadly expressed in tissues such as the liver, immune cells, and epithelial tissues, where it regulates processes like cell proliferation, differentiation, and immune homeostasis. It has been implicated in regulating inflammation and epithelial repair during infections. Dysregulation of SOCS4 is linked to chronic inflammation, impaired wound healing, and cancer progression, where excessive EGFR signaling promotes uncontrolled cell proliferation. Knockdown studies reveal hyperactivated cytokine signaling, increased inflammatory responses, and abnormal cellular growth, highlighting its critical role in balancing cytokine-mediated signaling pathways.
Related Products
Human SOCS4(Suppressor Of Cytokine Signaling 4) ELISA Kit
Ver Producto
Suppressor of Cytokine Signaling 4 (SOCS4) Antibody
SOCS4 Antibody is a Rabbit Polyclonal Antibody against SOCS4.
Ver Producto
Suppressor of Cytokine Signaling 4 (SOCS4) Antibody
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Ver Producto