Human Slam Family Member 6 (SLAMF6) Protein

546€ (100 µg)
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935106861
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name
Human Slam Family Member 6 (SLAMF6) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx620567
tested applications
ELISA, WB, SDS-PAGE
Description
Human Slam Family Member 6 (SLAMF6) Protein is a recombinant Human protein produced in a Mammalian cell expression system.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides  | 
| Immunogen Target | Slam Family Member 6 (SLAMF6)  | 
| Host | Mammalian cells  | 
| Origin | Human  | 
| Conjugation | Unconjugated  | 
| Observed MW | Molecular Weight: Calculated MW: 26.43 kDa Sequence Fragment: Met1-Met226 Tag: C-terminal His tag  | 
| Expression | Recombinant  | 
| Purity | > 90% (SDS-PAGE)  | 
| Size 1 | 100 µg  | 
| Size 2 | 1 mg  | 
| Form | Liquid  | 
| Tested Applications | ELISA, WB, SDS-PAGE  | 
| Buffer | 0.01 M PBS, pH 7.4.  | 
| Availability | Shipped within 5-12 working days.  | 
| Storage | Store at 2-8 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C for long-term storage. Avoid repeated freeze-thaw cycles.  | 
| Dry Ice | No  | 
| UniProt ID | Q96DU3  | 
| Alias | Activating NK receptor,KALI,NTBA,CD352,KALIb,Ly108,NTB-A,SF2000,NK-T-B-antigen  | 
| Background | Protein SLAMF6  | 
| Note | This product is for research use only. This product is shipped with ice packs. Not for human consumption, cosmetic, therapeutic or diagnostic use.  | 
Descripción
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The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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