Human SLAM family member 6 (SLAMF6) ELISA Kit
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Description
Human SLAM family member 6 (SLAMF6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human SLAM family member 6 (SLAMF6) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | SLAM family member 6 (SLAMF6) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96DU3 |
| OMIM | 606446 |
| Alias | Activating NK receptor,KALI,NTBA,CD352,KALIb,Ly108,NTB-A,SF2000,NK-T-B-antigen |
| Background | Elisa kits for SLAMF6 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
SLAMF6 (Signaling Lymphocytic Activation Molecule Family Member 6) is a surface receptor protein primarily expressed on cells of the immune system, including T cells, B cells, natural killer (NK) cells, and dendritic cells. SLAMF6 is part of the SLAM family, which belongs to the immunoglobulin (Ig) superfamily. SLAM receptors are involved in the regulation of immune responses and play a role in cellular communication during immune activation, regulation, and self-tolerance. SLAMF6 functions as a self-ligand, meaning it binds to another SLAMF6 molecule on an adjacent cell to mediate its effects, thus promoting homophilic interactions that help coordinate immune cell interactions and responses. SLAMF6 has a key role in modulating T cell and NK cell activation, helping maintain immune homeostasis and contributing to immune tolerance mechanisms. It achieves these functions by signaling through its intracellular tail, which contains motifs that interact with downstream signaling molecules, notably SAP (SLAM-associated protein). SAP is a critical adapter molecule that enables SLAMF6 to signal effectively in immune cells, primarily influencing pathways involved in cell activation, differentiation, and cytokine production.
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