Human Signaling Threshold-Regulating Transmembrane Adapter 1 (SIT1) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for SIT1
proveedor
Abbexareference
abx545965Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Signaling Threshold-Regulating Transmembrane Adapter 1 (SIT1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Signaling Threshold-Regulating Transmembrane Adapter 1 (SIT1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Signaling Threshold-Regulating Transmembrane Adapter 1 (SIT1), also known as SIT, is an immunoregulatory protein primarily expressed in T cells. It acts as a transmembrane adaptor involved in modulating T-cell receptor (TCR) signaling by interacting with key intracellular signaling molecules such as Src family kinases and SH2 domain-containing phosphatases. SIT1 fine-tunes immune responses by negatively regulating TCR-mediated activation, thus maintaining immune tolerance and preventing overactivation that could lead to autoimmune diseases. Its dysregulation is associated with immune disorders and may affect T-cell maturation and peripheral immune homeostasis.
Características del producto
category
ELISA Kits
immunogen target
Signaling Threshold-Regulating Transmembrane Adapter 1 (SIT1)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.05 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
SIT1, SIT, SIT-R, signaling threshold regulating transmembrane adaptor 1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
SIT1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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