Human SIGLEC5(Sialic acid-binding Ig-like lectin 5) ELISA Kit

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Product specifications
Category | ELISA Kits |
Reactivity | human |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 0.156-10ng/ml |
Size 1 | 96T |
Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 6 months |
UniProt ID | O15389 |
Alias | CD170,OBBP2,CD33L2,OB-BP2,SIGLEC-5,Obesity-binding protein 2,CD33 antigen-like 2 |
Background | Elisa Kits SIGLEC5 |
Status | RUO |
SIGLEC5 is an inhibitory receptor expressed on monocytes, neutrophils, and B cells. It binds to sialic acid-containing glycans on host and microbial surfaces, modulating immune responses to avoid excessive inflammation. Through its immunoreceptor tyrosine-based inhibitory motifs (ITIMs), SIGLEC5 dampens activation signals and helps maintain immune tolerance. This protein also plays a role in preventing inappropriate immune responses during pregnancy and infection. Genetic fusion events between SIGLEC5 and SIGLEC14 have been noted, affecting the functional balance between activation and inhibition. SIGLEC5 is studied for its involvement in autoimmune diseases and infections.
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