Human SIGLEC5(Sialic acid-binding Ig-like lectin 5) ELISA Kit

Este producto es parte de SIGLEC - sialic acid binding Ig like lectin
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935106861
info@markelab.com
name
Human SIGLEC5(Sialic acid-binding Ig-like lectin 5) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH12291

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Data sheet

Product specifications

CategoryELISA Kits
Reactivityhuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich ELISA, Double Antibody
Test Range0.156-10ng/ml
Size 196T
Sample TypeSerum,Plasma,Tissue homogenates,Other biological fluids
AvailabilityShipped within 10-14 working days.
Storage2-8 °C for 6 months
UniProt IDO15389
AliasCD170,OBBP2,CD33L2,OB-BP2,SIGLEC-5,Obesity-binding protein 2,CD33 antigen-like 2
BackgroundElisa Kits SIGLEC5
StatusRUO

SIGLEC5 is an inhibitory receptor expressed on monocytes, neutrophils, and B cells. It binds to sialic acid-containing glycans on host and microbial surfaces, modulating immune responses to avoid excessive inflammation. Through its immunoreceptor tyrosine-based inhibitory motifs (ITIMs), SIGLEC5 dampens activation signals and helps maintain immune tolerance. This protein also plays a role in preventing inappropriate immune responses during pregnancy and infection. Genetic fusion events between SIGLEC5 and SIGLEC14 have been noted, affecting the functional balance between activation and inhibition. SIGLEC5 is studied for its involvement in autoimmune diseases and infections.

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Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5) Antibody

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